Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | KDM1A | O60341 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4624670 | 1.00 | HTR2A (0.42) | HTR2AKDM1AMEN1KMT2AGAA | |
| SCHEMBL30065822 | 1.00 | HTR2A (0.42) | HTR2AKDM1AMEN1KMT2AGAA | |
| SCHEMBL12955323 | 1.00 | HTR2A (0.42) | HTR2AKDM1AMEN1KMT2AGAA | |
| SCHEMBL2481266 | 1.00 | HTR2A (0.42) | HTR2AKDM1AMEN1KMT2AGAA | |
| SCHEMBL11869101 | 0.81 | KDM1A (0.38) | HTR2AKDM1AMEN1KMT2AGAA | |
| SCHEMBL29436947 | 0.78 | EDNRA (0.43) | HTR2AMEN1KMT2AGAAEDNRA | |
| SCHEMBL8850719 | 0.72 | HTR2A (0.60) | HTR2AKDM1AMEN1KMT2AGAA | |
| SCHEMBL545454 | 0.70 | MEN1 (0.53) | HTR2AKDM1AMEN1KMT2AGAA | |
| SCHEMBL29490140 | 0.70 | MEN1 (0.53) | HTR2AKDM1AMEN1KMT2AGAA | |
| Methane SCHEMBL5316271 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8691998-B2 | Catalysts containing N-heterocyclic carbenes for enantioselective synthesis | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2014-04-08 | — | — | US | claimed |
| US-20130190508-A1 | CATALYSTS CONTAINING N-HETEROCYCLIC CARBENES FOR ENANTIOSELECTIVE SYNTHESIS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-07-25 | — | — | US | claimed |
| US-20100292465-A1 | CATALYSTS CONTAINING N-HETEROCYCLIC CARBENES FOR ENANTIOSELECTIVE SYNTHESIS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-11-18 | — | — | US | claimed |
| US-8717565-B2 | Optically active functional fluid markers | THE LUBRIZOL CORPORATION (US) | 2014-05-06 | — | — | US | disclosed |
| US-8691998-B2 | Catalysts containing N-heterocyclic carbenes for enantioselective synthesis | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2014-04-08 | — | — | US | disclosed |
| US-20130190508-A1 | CATALYSTS CONTAINING N-HETEROCYCLIC CARBENES FOR ENANTIOSELECTIVE SYNTHESIS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-07-25 | — | — | US | disclosed |
| US-8455661-B2 | Catalysts containing N-heterocyclic carbenes for enantioselective synthesis | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-06-04 | — | — | US | disclosed |
| EP-2376894-A1 | OPTICALLY ACTIVE FUNCTIONAL FLUID MARKERS | The Lubrizol Corporation (US) | 2011-10-19 | — | — | EP | disclosed |
| EP-2373977-A1 | OPTICALLY ACTIVE FUNCTIONAL FLUID MARKERS | The Lubrizol Corporation (US) | 2011-10-12 | — | — | EP | disclosed |
| US-20100292465-A1 | CATALYSTS CONTAINING N-HETEROCYCLIC CARBENES FOR ENANTIOSELECTIVE SYNTHESIS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-11-18 | — | — | US | disclosed |
| WO-2010077753-A1 | OPTICALLY ACTIVE FUNCTIONAL FLUID MARKERS | THE LUBRIZOL CORPORATION (US) | 2010-07-08 | — | — | WO | disclosed |
| WO-2010077754-A1 | OPTICALLY ACTIVE FUNCTIONAL FLUID MARKERS | THE LUBRIZOL CORPORATION (US) | 2010-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292465-A1 | CATALYSTS CONTAINING N-HETEROCYCLIC CARBENES FOR ENANTIOSELECTIVE SYNTHESIS | NDC1, NBAS, NIT2 | HTR2A 418/4885KDM1A 3629/4885MEN1 1064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.