Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 12/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.35 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24814021 | 1.00 | USP7 (0.59) | USP7HPGDTSHRCHRNB2CHRNA3 | |
| SCHEMBL23911381 | 0.86 | USP7 (0.45) | USP7HPGDTSHR | |
| SCHEMBL23911385 | 0.86 | USP7 (0.45) | USP7HPGDTSHR | |
| SCHEMBL24813979 | 0.83 | USP7 (0.43) | USP7HPGDTSHR | |
| SCHEMBL23911248 | 0.82 | USP7 (0.43) | USP7HPGDTSHR | |
| SCHEMBL23911386 | 0.81 | USP7 (0.41) | USP7HPGD | |
| SCHEMBL15708203 | 0.78 | USP7 (0.53) | USP7HPGDTSHRHRH4 | |
| SCHEMBL23910855 | 0.77 | SMN1; SMN2 (0.40) | USP7 | |
| SCHEMBL23911362 | 0.77 | SIRT2 (0.38) | USP7 | |
| SCHEMBL23910858 | 0.77 | SMN1; SMN2 (0.40) | USP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272133-A2 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP7 LIGANDS | Stablix, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |