SCHEMBL23911385

SCHEMBL23911385

O=C(O)N1CCN(C(=O)C2Cc3cc(Cl)cc(Br)c3O2)CC1

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 12/20 0.45
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
GAA P10253 1/20 0.34
SIRT2 Q8IXJ6 4/20 0.33
CNR1 P21554 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23911381 1.00 USP7 (0.45) USP7HPGDTSHRGAASIRT2
SCHEMBL23911615 0.88 USP7 (0.36) USP7CNR1
SCHEMBL23911618 0.88 USP7 (0.36) USP7CNR1
SCHEMBL24813979 0.87 USP7 (0.43) USP7HPGDTSHRSIRT2
SCHEMBL24814021 0.86 USP7 (0.59) USP7HPGDTSHR
SCHEMBL24813008 0.86 USP7 (0.59) USP7HPGDTSHR
SCHEMBL23911248 0.86 USP7 (0.43) USP7HPGDTSHRGAASIRT2
SCHEMBL23911386 0.84 USP7 (0.41) USP7HPGD
SCHEMBL23910858 0.81 SMN1; SMN2 (0.40) USP7SIRT2
SCHEMBL23910855 0.81 SMN1; SMN2 (0.40) USP7SIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210317134-A1 UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF RAPT THERAPEUTICS INC (US) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210317134-A1 UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF USP7, SENP7, USP8 USP7 1/4885HPGD 3395/4885TSHR 3825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.