Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26340944 | 0.82 | JAK2 (0.33) | KMT2AJAK2TYK2JAK3CYP4F2 | |
| SCHEMBL16810224 | 0.81 | JAK2 (0.34) | KMT2AJAK2TYK2JAK3TDP1 | |
| SCHEMBL25604082 | 0.78 | JAK2 (0.32) | JAK2TYK2JAK3 | |
| SCHEMBL2612382 | 0.78 | JAK2 (0.34) | KMT2AJAK2TYK2JAK3 | |
| SCHEMBL3765275 | 0.76 | NPC1 (0.36) | KMT2AJAK2TYK2JAK3 | |
| SCHEMBL21672546 | 0.76 | GABRA1 (0.50) | KMT2AJAK2TYK2JAK3 | |
| SCHEMBL2806055 | 0.76 | JAK2 (0.33) | KMT2AJAK2TYK2JAK3 | |
| SCHEMBL4762523 | 0.76 | ESR1 (0.34) | KMT2AJAK2TYK2JAK3 | |
| Hydrochloric Acid SCHEMBL3764110 | 0.74 | JAK2 (0.33) | KMT2AJAK2TYK2JAK3 | |
| SCHEMBL18444926 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272133-A2 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP7 LIGANDS | Stablix, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |