⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30835718 | 0.73 | PLAU (0.35) | — | |
| SCHEMBL192582 | 0.72 | AGXT (0.47) | — | |
| SCHEMBL24811482 | 0.71 | CA2 (0.31) | — | |
| SCHEMBL24811122 | 0.71 | — | — | |
| SCHEMBL24814028 | 0.70 | MAPT (0.31) | — | |
| SCHEMBL1577309 | 0.70 | AAK1 (0.32) | — | |
| SCHEMBL10179826 | 0.69 | TDP1 (0.35) | — | |
| SCHEMBL21958080 | 0.68 | MAPT (0.31) | — | |
| SCHEMBL17841622 | 0.68 | CHRM2 (0.33) | — | |
| SCHEMBL29950898 | 0.68 | AGXT (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272133-A2 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP7 LIGANDS | Stablix, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |