Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2481406 | 1.00 | KMT2A (0.49) | KMT2AMEN1HTTLMNAUSP2 | |
| SCHEMBL2481404 | 1.00 | KMT2A (0.49) | KMT2AMEN1HTTLMNAUSP2 | |
| SCHEMBL12497665 | 0.83 | MEN1 (0.54) | KMT2AMEN1HTTLMNAUSP2 | |
| SCHEMBL19900669 | 0.79 | SLC6A3 (0.38) | KMT2AMEN1HTTLMNAHPGD | |
| SCHEMBL3070892 | 0.78 | — | — | |
| SCHEMBL3068352 | 0.78 | — | — | |
| SCHEMBL3070889 | 0.78 | — | — | |
| SCHEMBL3062278 | 0.78 | — | — | |
| SCHEMBL3068358 | 0.78 | — | — | |
| SCHEMBL3867748 | 0.76 | CHRM2 (0.31) | KMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385109-B1 | A group of esterases for the enantioselective production of fine and speciality chemicals | BRAIN BIOTECHNOLOGY RES & INFORMATION NETWORK AG (DE) | 2015-12-02 | — | — | EP | disclosed |
| EP-2377930-B1 | A group of esterases for the enantioselective production of fine and speciality chemicals | BRAIN BIOTECHNOLOGY RES & INFORMATION NETWORK AG (DE) | 2015-12-02 | — | — | EP | disclosed |
| US-9193961-B2 | Polynucleotides encoding enantioselective carboxylesterases and methods of making same | B.R.A.I.N. AG (DE) | 2015-11-24 | — | — | US | disclosed |
| EP-2013337-B1 | A GROUP OF ESTERASES FOR THE ENANTIOSELECTIVE PRODUCTION OF FINE AND SPECIALITY CHEMICALS | BRAIN BIOTECHNOLOGY RES & INFORMATION NETWORK AG (DE) | 2013-03-27 | — | — | EP | disclosed |
| EP-2385109-A2 | A group of esterases for the enantioselective production of fine and speciality chemicals | B.R.A.I.N. Biotechnology Research And Information Network AG (DE) | 2011-11-09 | — | — | EP | disclosed |
| EP-2377930-A1 | A group of esterases for the enantioselective production of fine and speciality chemicals | B.R.A.I.N. Biotechnology Research And Information Network AG (DE) | 2011-10-19 | — | — | EP | disclosed |
| US-20090311745-A1 | GROUP OF ESTERASES FOR THE ENANTIOSELECTIVE PRODUCTION OF FINE AND SPECIALITY CHEMICALS | B.R.A.I.N AG (DE) | 2009-12-17 | — | — | US | disclosed |
| EP-2013337-A2 | A GROUP OF ESTERASES FOR THE ENANTIOSELECTIVE PRODUCTION OF FINE AND SPECIALITY CHEMICALS | B.R.A.I.N. AG (DE) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007128496-A2 | A GROUP OF ESTERASES FOR THE ENANTIOSELECTIVE PRODUCTION OF FINE AND SPECIALITY CHEMICALS | B.R.A.I.N. AG (DE) | 2007-11-15 | — | — | WO | disclosed |