SCHEMBL24814643

SCHEMBL24814643

c1ccc(-c2ccc(N(c3ccc(-c4ccc(-c5ccc6ccccc6c5)cc4)cc3)c3cccc(-c4ccc5ccccc5c4)c3)c(-c3ccccc3)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 2/20 0.41
HSD17B2 P37059 2/20 0.41
ESR1 P03372 3/20 0.40
ESR2 Q92731 3/20 0.40
ACMSD Q8TDX5 1/20 0.37
GSTP1 P09211 1/20 0.37
CYP17A1 P05093 1/20 0.36
CYP19A1 P11511 1/20 0.36
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
ALOX5 P09917 3/20 0.36
BACE1 P56817 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
CYP1A1 P04798 1/20 0.35
CYP1B1 Q16678 1/20 0.35
NPC1 O15118 1/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24814645 0.96 HSD17B1 (0.39) HSD17B1HSD17B2ESR1ESR2ACMSD
SCHEMBL22436003 0.96 HSD17B1 (0.42) HSD17B1HSD17B2ESR1ESR2ACMSD
SCHEMBL22436017 0.96 ESR1 (0.43) HSD17B1HSD17B2ESR1ESR2ACMSD
SCHEMBL22435606 0.94 HSD17B1 (0.44) HSD17B1HSD17B2ESR1ESR2ACMSD
SCHEMBL22435607 0.94 ESR1 (0.44) HSD17B1HSD17B2ESR1ESR2ACMSD
SCHEMBL22435740 0.93 HSD17B1 (0.39) HSD17B1HSD17B2ESR1ESR2ACMSD
SCHEMBL22435752 0.93 ESR1 (0.40) HSD17B1HSD17B2ESR1ESR2ACMSD
SCHEMBL21203691 0.93 ESR1 (0.44) HSD17B1HSD17B2ESR1ESR2GSTP1
SCHEMBL24918438 0.91 HSD17B1 (0.41) HSD17B1HSD17B2ESR1ESR2ACMSD
SCHEMBL24918538 0.91 HSD17B1 (0.41) HSD17B1HSD17B2ESR1ESR2ACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022270296-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2022-12-29 WO disclosed