Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30050173 | 1.00 | CYP1A2 (0.47) | CYP1A2SMN1; SMN2LMNACYP2C19TDP1 | |
| SCHEMBL6247750 | 0.82 | PTPRA (0.51) | CYP1A2SMN1; SMN2LMNATDP1HRH3 | |
| SCHEMBL6247756 | 0.82 | PTPRA (0.51) | CYP1A2SMN1; SMN2LMNATDP1HRH3 | |
| SCHEMBL27734507 | 0.82 | CYP1A2 (0.51) | CYP1A2SMN1; SMN2LMNACYP2C19TDP1 | |
| SCHEMBL28078250 | 0.82 | CYP1A2 (0.55) | CYP1A2SMN1; SMN2CYP2C19TDP1HRH1 | |
| SCHEMBL28078253 | 0.82 | CYP1A2 (0.55) | CYP1A2SMN1; SMN2CYP2C19TDP1HRH1 | |
| SCHEMBL27734504 | 0.82 | CYP1A2 (0.51) | CYP1A2SMN1; SMN2LMNACYP2C19TDP1 | |
| Hydrochloric Acid SCHEMBL28915552 | 0.81 | PTPRA (0.50) | CYP1A2SMN1; SMN2LMNATDP1HRH3 | |
| Hydrochloric Acid SCHEMBL7897236 | 0.81 | PTPRA (0.50) | CYP1A2SMN1; SMN2LMNATDP1HRH3 | |
| Hydrochloric Acid SCHEMBL8389822 | 0.81 | PTPRA (0.50) | CYP1A2SMN1; SMN2LMNATDP1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230121337-A1 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. | 2023-04-20 | — | — | US | disclosed |
| WO-2022272106-A1 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230121337-A1 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CDK2, CDK20, CDK2AP2 | CYP1A2 3613/4885SMN1; SMN2 1898/4885LMNA 1270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.