Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.67 |
| ▸ | CTSS | P25774 | 9/20 | 0.67 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18467225 | 1.00 | CTSK (0.67) | CTSKCTSSCTSLCTSBCYP1A2 | |
| SCHEMBL9029356 | 0.90 | CTSK (0.68) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL13560716 | 0.90 | CTSK (0.68) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL29979228 | 0.87 | CTSK (0.51) | CTSKCTSSCTSLCTSBCYP1A2 | |
| SCHEMBL8140278 | 0.87 | CTSK (0.67) | CTSKCTSSCTSLCTSBCYP1A2 | |
| SCHEMBL16255614 | 0.86 | CTSK (0.65) | CTSKCTSSCTSLCTSBCYP1A2 | |
| SCHEMBL24815320 | 0.86 | CTSK (0.65) | CTSKCTSSCTSLCTSBCYP1A2 | |
| SCHEMBL30660249 | 0.86 | CTSK (0.65) | CTSKCTSSCTSLCTSBCYP1A2 | |
| SCHEMBL7762812 | 0.85 | CTSK (0.50) | CTSKCTSSCTSLCTSBCYP1A2 | |
| SCHEMBL7762815 | 0.85 | CTSK (0.50) | CTSKCTSSCTSLCTSBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272106-A1 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2022-12-29 | — | — | WO | disclosed |