SCHEMBL24815567

SCHEMBL24815567

CN1CCC(=C(F)Br)CC1

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SETD7 Q8WTS6 2/20 0.42
DRD2 P14416 2/20 0.33
DRD1 P21728 2/20 0.33
DRD5 P21918 2/20 0.33
DRD3 P35462 2/20 0.33
MAOA P21397 2/20 0.33
MAOB P27338 2/20 0.33
DPP7 Q9UHL4 1/20 0.33
DRD4 P21917 1/20 0.33
NOS1 P29475 1/20 0.32
HTR1F P30939 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14589051 0.79 SETD7 (0.45) SETD7DRD2DRD1DRD5DRD3
SCHEMBL24815575 0.79 SETD7 (0.45) SETD7DRD2DRD1DRD5DRD3
SCHEMBL24815586 0.77 SETD7 (0.43) SETD7DRD2DRD1DRD5DRD3
SCHEMBL24815568 0.75 SETD7 (0.42) SETD7DRD2DRD1DRD5DRD3
SCHEMBL24816956 0.75 CHRNA7 (0.47)
SCHEMBL24815569 0.71 SETD7 (0.39) SETD7DRD2DRD1DRD5DRD3
SCHEMBL13006727 0.70 SETD7 (0.46) SETD7DRD2DRD1DRD5DRD3
SCHEMBL24815576 0.70
SCHEMBL22036848 0.69 SETD7 (0.45) SETD7DRD2DRD1DRD5DRD3
SCHEMBL14262771 0.66 SETD7 (0.67) SETD7DRD2DRD1DRD5DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022268230-A1 COMPOUND AS KIF18A INHIBITOR 杭州英创医药科技有限公司 2022-12-29 WO disclosed