Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 6/20 | 0.36 |
| ▸ | DRD1 | P21728 | 6/20 | 0.36 |
| ▸ | DRD5 | P21918 | 6/20 | 0.36 |
| ▸ | DRD3 | P35462 | 5/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24815567 | 0.79 | SETD7 (0.42) | SETD7DRD2DRD1DRD5DRD3 | |
| SCHEMBL13006727 | 0.74 | SETD7 (0.46) | SETD7DRD2DRD1DRD5DRD3 | |
| SCHEMBL22036848 | 0.72 | SETD7 (0.45) | SETD7DRD2DRD1DRD5DRD3 | |
| SCHEMBL14589051 | 0.72 | SETD7 (0.45) | SETD7DRD2DRD1DRD5DRD3 | |
| SCHEMBL14720933 | 0.72 | GRIN2D (0.31) | — | |
| SCHEMBL24815586 | 0.70 | SETD7 (0.43) | SETD7DRD2DRD1DRD5DRD3 | |
| SCHEMBL14262771 | 0.69 | SETD7 (0.67) | SETD7DRD2DRD1DRD5DRD3 | |
| SCHEMBL24815568 | 0.69 | SETD7 (0.42) | SETD7DRD2DRD1DRD5DRD3 | |
| SCHEMBL1285125 | 0.67 | — | — | |
| SCHEMBL24815664 | 0.66 | GPR183 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268230-A1 | COMPOUND AS KIF18A INHIBITOR | 杭州英创医药科技有限公司 | 2022-12-29 | — | — | WO | disclosed |