Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF18A | Q8NI77 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24815639 | 1.00 | KIF18A (0.75) | KIF18A | |
| SCHEMBL24815640 | 1.00 | KIF18A (0.75) | KIF18A | |
| SCHEMBL24816964 | 0.94 | KIF18A (0.85) | KIF18A | |
| SCHEMBL24816965 | 0.94 | KIF18A (0.85) | KIF18A | |
| SCHEMBL24816968 | 0.94 | KIF18A (0.85) | KIF18A | |
| SCHEMBL24818180 | 0.89 | KIF18A (0.86) | KIF18A | |
| SCHEMBL24817152 | 0.89 | KIF18A (0.82) | KIF18A | |
| SCHEMBL24817338 | 0.88 | KIF18A (0.83) | KIF18A | |
| SCHEMBL24816962 | 0.88 | KIF18A (0.84) | KIF18A | |
| SCHEMBL24815899 | 0.87 | KIF18A (0.84) | KIF18A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268230-A1 | COMPOUND AS KIF18A INHIBITOR | 杭州英创医药科技有限公司 | 2022-12-29 | — | — | WO | disclosed |