Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601555 | 0.90 | TNIK (0.34) | PTAFR | |
| SCHEMBL24721217 | 0.89 | PTAFR (0.31) | PTAFR | |
| SCHEMBL24721471 | 0.86 | — | — | |
| SCHEMBL29909164 | 0.83 | PTAFR (0.32) | PTAFR | |
| SCHEMBL23577576 | 0.83 | PTAFR (0.32) | PTAFR | |
| SCHEMBL23601469 | 0.82 | NQO2 (0.32) | PTAFR | |
| SCHEMBL24814734 | 0.81 | PTAFR (0.30) | PTAFR | |
| SCHEMBL30048944 | 0.81 | PTAFR (0.30) | PTAFR | |
| SCHEMBL29909080 | 0.78 | — | — | |
| SCHEMBL23601554 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359415-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022271684-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
| WO-2022271684-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-12-29 | — | — | WO | disclosed |