Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 13/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.32 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19062737 | 0.77 | GRM5 (0.39) | GRM5NOS3NOS2NOS1ASIC3 | |
| SCHEMBL14207818 | 0.77 | GRM5 (0.42) | GRM5NOS3NOS2NOS1ASIC3 | |
| SCHEMBL10130898 | 0.72 | GRM5 (0.48) | GRM5NOS3NOS2MCHR1NOS1 | |
| SCHEMBL17039219 | 0.70 | NOS3 (0.46) | GRM5NOS3NOS2MCHR1NOS1 | |
| SCHEMBL17036489 | 0.69 | NOS3 (0.42) | GRM5NOS3NOS2MCHR1ASIC3 | |
| SCHEMBL19584510 | 0.69 | GRM5 (0.39) | GRM5NOS3NOS2 | |
| SCHEMBL29162208 | 0.69 | NOS3 (0.32) | NOS3NOS2 | |
| SCHEMBL2714786 | 0.68 | NOS3 (0.45) | GRM5NOS3NOS2MCHR1NOS1 | |
| SCHEMBL8115895 | 0.67 | GRM5 (0.61) | GRM5ASIC3 | |
| SCHEMBL24817126 | 0.67 | SCN9A (0.40) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268230-A1 | COMPOUND AS KIF18A INHIBITOR | 杭州英创医药科技有限公司 | 2022-12-29 | — | — | WO | disclosed |