Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLB1 | P16278 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24818644 | 1.00 | GLB1 (0.35) | GLB1HTTEPHX1CYP2D6CYP2C19 | |
| SCHEMBL24818651 | 1.00 | GLB1 (0.35) | GLB1HTTEPHX1CYP2D6CYP2C19 | |
| SCHEMBL24819155 | 1.00 | GLB1 (0.35) | GLB1HTTEPHX1CYP2D6CYP2C19 | |
| SCHEMBL24819138 | 1.00 | GLB1 (0.35) | GLB1HTTEPHX1CYP2D6CYP2C19 | |
| SCHEMBL24819140 | 0.86 | HTT (0.40) | GLB1HTTEPHX1 | |
| SCHEMBL24820161 | 0.86 | HTR1A (0.36) | GLB1HTTEPHX1 | |
| SCHEMBL24819149 | 0.86 | HTT (0.40) | GLB1HTTEPHX1 | |
| SCHEMBL24819131 | 0.86 | HTT (0.40) | GLB1HTTEPHX1 | |
| SCHEMBL24819143 | 0.86 | HTT (0.40) | GLB1HTTEPHX1 | |
| SCHEMBL24842080 | 0.86 | HTR1A (0.36) | GLB1HTTEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |