Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | CBLB | Q13191 | 12/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152828 | 1.00 | CNR2 (0.42) | CNR2CBLBCNR1GRM2KCNH2 | |
| SCHEMBL24818660 | 0.89 | CBLB (0.42) | CNR2CBLB | |
| SCHEMBL30152576 | 0.89 | CBLB (0.42) | CNR2CBLB | |
| SCHEMBL30153085 | 0.86 | CBLB (0.36) | CNR2CBLBCNR1 | |
| SCHEMBL24818860 | 0.86 | CBLB (0.36) | CNR2CBLBCNR1 | |
| SCHEMBL30153086 | 0.86 | CBLB (0.36) | CNR2CBLBCNR1 | |
| SCHEMBL24819893 | 0.86 | CBLB (0.40) | CNR2CBLBGRM2KCNH2 | |
| SCHEMBL24818677 | 0.86 | CBLB (0.40) | CNR2CBLBGRM2KCNH2 | |
| SCHEMBL29190140 | 0.85 | CNR2 (0.40) | CNR2CBLBCNR1GRM2KCNH2 | |
| SCHEMBL29190139 | 0.85 | CNR2 (0.40) | CNR2CBLBCNR1GRM2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |