Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | CETP | P11597 | 3/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | CBLB | Q13191 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153040 | 1.00 | HPGD (0.37) | HPGDCETPCLK1SMN1; SMN2VSIR | |
| SCHEMBL30792096 | 1.00 | HPGD (0.37) | HPGDCETPCLK1SMN1; SMN2VSIR | |
| SCHEMBL30153029 | 0.95 | HPGD (0.37) | HPGDCETPCLK1SMN1; SMN2VSIR | |
| SCHEMBL24820064 | 0.95 | HPGD (0.37) | HPGDCETPCLK1SMN1; SMN2VSIR | |
| SCHEMBL30153258 | 0.94 | HPGD (0.37) | HPGDCETPCLK1SMN1; SMN2VSIR | |
| SCHEMBL24821895 | 0.94 | HPGD (0.37) | HPGDCETPCLK1SMN1; SMN2VSIR | |
| SCHEMBL24819809 | 0.92 | CETP (0.38) | HPGDCETPCLK1SMN1; SMN2S1PR1 | |
| SCHEMBL30153136 | 0.92 | CETP (0.38) | HPGDCETPCLK1SMN1; SMN2S1PR1 | |
| SCHEMBL24818914 | 0.91 | HPGD (0.37) | HPGDCETPCLK1SMN1; SMN2VSIR | |
| SCHEMBL24818726 | 0.91 | HPGD (0.37) | HPGDCETPVSIRS1PR1CBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |