Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.37 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.35 |
| ▸ | CBLB | Q13191 | 3/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152816 | 1.00 | HPGD (0.37) | HPGDS1PR1HPSECBLBCETP | |
| SCHEMBL24818914 | 0.94 | HPGD (0.37) | HPGDS1PR1CBLBCETPSCN9A | |
| SCHEMBL30153353 | 0.92 | SCN9A (0.38) | S1PR1CBLBCETPSCN9AS1PR3 | |
| SCHEMBL24818728 | 0.92 | SCN9A (0.38) | S1PR1CBLBCETPSCN9AS1PR3 | |
| SCHEMBL30153040 | 0.91 | HPGD (0.37) | HPGDS1PR1HPSECBLBCETP | |
| SCHEMBL30792096 | 0.91 | HPGD (0.37) | HPGDS1PR1HPSECBLBCETP | |
| SCHEMBL24818673 | 0.91 | HPGD (0.37) | HPGDS1PR1HPSECBLBCETP | |
| SCHEMBL24819726 | 0.91 | HPGD (0.39) | HPGDCBLBCETPVSIRLMNA | |
| SCHEMBL24819725 | 0.89 | HPGD (0.34) | HPGDS1PR1HPSECBLBCETP | |
| SCHEMBL24818951 | 0.87 | ESR2 (0.34) | HPGDS1PR1CBLBCETPSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |