Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 8/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.33 |
| ▸ | CBLB | Q13191 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.32 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.32 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24820738 | 0.91 | NPC1 (0.35) | S1PR1S1PR3CBLBPDCD1CD274 | |
| SCHEMBL30152736 | 0.90 | CBLB (0.37) | S1PR1CBLBPDCD1CD274HPSE | |
| SCHEMBL24820525 | 0.90 | CBLB (0.37) | S1PR1CBLBPDCD1CD274HPSE | |
| SCHEMBL24820602 | 0.88 | CBLB (0.42) | CBLBPDCD1CD274CETPHPSE | |
| SCHEMBL30153100 | 0.88 | CBLB (0.42) | CBLBPDCD1CD274CETPHPSE | |
| SCHEMBL30152929 | 0.88 | CBLB (0.33) | CBLBMAP3K5 | |
| SCHEMBL30153055 | 0.88 | CBLB (0.33) | CBLBPDCD1CD274MAP3K5 | |
| SCHEMBL24820581 | 0.88 | CBLB (0.33) | CBLBMAP3K5 | |
| SCHEMBL24818816 | 0.88 | CBLB (0.33) | CBLBPDCD1CD274MAP3K5 | |
| SCHEMBL24819948 | 0.88 | S1PR1 (0.35) | S1PR1S1PR3PDCD1CD274CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |