Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 13/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24820602 | 1.00 | CBLB (0.42) | CBLBCETPPPARGCYP11B1CYP11B2 | |
| SCHEMBL24820594 | 0.92 | CBLB (0.42) | CBLBCETPPPARGCYP11B1CYP11B2 | |
| SCHEMBL30152718 | 0.92 | CBLB (0.42) | CBLBCETPPPARGCYP11B1CYP11B2 | |
| SCHEMBL30152520 | 0.89 | CBLB (0.46) | CBLBCETPPPARGCYP11B1CYP11B2 | |
| SCHEMBL24821767 | 0.89 | CBLB (0.46) | CBLBCETPPPARGCYP11B1CYP11B2 | |
| SCHEMBL24820738 | 0.88 | NPC1 (0.35) | CBLBCETPHPSEPDCD1CD274 | |
| SCHEMBL24818776 | 0.88 | S1PR1 (0.33) | CBLBCETPHPSEPDCD1CD274 | |
| SCHEMBL30152733 | 0.87 | CBLB (0.43) | CBLBCYP11B1CYP11B2PDCD1CD274 | |
| SCHEMBL24818968 | 0.87 | CBLB (0.43) | CBLBCYP11B1CYP11B2PDCD1CD274 | |
| SCHEMBL24819950 | 0.87 | CBLB (0.44) | CBLBCETPPPARGPDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359381-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |