Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 13/20 | 0.42 |
| ▸ | CBLB | Q13191 | 2/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 5/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153193 | 1.00 | VSIR (0.42) | VSIRCBLBPDCD1CD274CETP | |
| SCHEMBL24819890 | 0.94 | VSIR (0.41) | VSIRCBLBPDCD1CD274CETP | |
| SCHEMBL24819846 | 0.94 | VSIR (0.39) | VSIRCBLBPDCD1CD274CETP | |
| SCHEMBL24818928 | 0.93 | VSIR (0.43) | VSIRCBLBPDCD1CD274CETP | |
| SCHEMBL30152605 | 0.93 | VSIR (0.43) | VSIRCBLBPDCD1CD274CETP | |
| SCHEMBL24820456 | 0.93 | VSIR (0.43) | VSIRCBLBPDCD1CD274CETP | |
| SCHEMBL24818699 | 0.92 | VSIR (0.38) | VSIRCBLBCETP | |
| SCHEMBL24821870 | 0.92 | VSIR (0.40) | VSIRCBLBPDCD1CD274CETP | |
| SCHEMBL30152947 | 0.92 | VSIR (0.40) | VSIRCBLBPDCD1CD274CETP | |
| SCHEMBL24819904 | 0.92 | VSIR (0.52) | VSIRPDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |