Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 5/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | CBLB | Q13191 | 4/20 | 0.36 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24822059 | 0.96 | PDCD1 (0.43) | PDCD1CD274S1PR1S1PR3CBLB | |
| SCHEMBL24819884 | 0.96 | PDCD1 (0.43) | PDCD1CD274S1PR1S1PR3CBLB | |
| SCHEMBL24818829 | 0.93 | CBLB (0.42) | S1PR1S1PR3PDE2ACBLBCNR2 | |
| SCHEMBL24820117 | 0.91 | HRH1 (0.41) | S1PR1S1PR3PDE2ACBLBTP53 | |
| SCHEMBL30152972 | 0.91 | HRH1 (0.41) | S1PR1S1PR3PDE2ACBLBTP53 | |
| SCHEMBL24818393 | 0.91 | HRH1 (0.41) | S1PR1S1PR3PDE2ACBLBTP53 | |
| SCHEMBL24820104 | 0.91 | HRH1 (0.41) | S1PR1S1PR3PDE2ACBLBTP53 | |
| SCHEMBL24818755 | 0.89 | GRM2 (0.38) | PDCD1CD274S1PR1S1PR3PDE2A | |
| SCHEMBL24818663 | 0.87 | CBLB (0.40) | CBLB | |
| SCHEMBL24819893 | 0.87 | CBLB (0.40) | PDCD1CD274S1PR1S1PR3CBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |