Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 14/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 10/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 10/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153006 | 1.00 | VSIR (0.41) | VSIRKCNH2CYP2D6GRIN2BPDCD1 | |
| SCHEMBL30153084 | 0.97 | VSIR (0.40) | VSIRKCNH2CYP2D6GRIN2BPDCD1 | |
| SCHEMBL30152568 | 0.97 | VSIR (0.40) | VSIRKCNH2CYP2D6GRIN2BPDCD1 | |
| SCHEMBL24820273 | 0.97 | VSIR (0.40) | VSIRKCNH2CYP2D6GRIN2BPDCD1 | |
| SCHEMBL24820155 | 0.97 | VSIR (0.40) | VSIRKCNH2CYP2D6GRIN2BPDCD1 | |
| SCHEMBL24818735 | 0.94 | VSIR (0.40) | VSIRKCNH2CYP2D6GRIN2BPDCD1 | |
| SCHEMBL24819925 | 0.91 | VSIR (0.40) | VSIRKCNH2PDCD1CD274 | |
| SCHEMBL30152858 | 0.91 | VSIR (0.40) | VSIRKCNH2PDCD1CD274 | |
| SCHEMBL24818944 | 0.90 | ATM (0.40) | VSIRKCNH2PDCD1CD274 | |
| SCHEMBL24821759 | 0.90 | ATM (0.40) | VSIRKCNH2PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |