Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 5/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 14/20 | 0.44 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30718659 | 0.88 | CRBN (0.46) | IKZF2CRBNIKZF1DDB1CSNK1A1 | |
| SCHEMBL31413392 | 0.88 | CRBN (0.46) | IKZF2CRBNIKZF1DDB1CSNK1A1 | |
| SCHEMBL24819318 | 0.87 | CRBN (0.56) | IKZF2CRBNIKZF1IKZF3 | |
| SCHEMBL20231489 | 0.86 | IKZF2 (0.51) | IKZF2CRBNDDB1CSNK1A1 | |
| SCHEMBL24818130 | 0.84 | CRBN (0.48) | IKZF2CRBNIKZF1 | |
| SCHEMBL24816831 | 0.84 | CRBN (0.48) | IKZF2CRBNIKZF1 | |
| SCHEMBL20231914 | 0.83 | CRBN (0.53) | IKZF2CRBNIKZF1DDB1IKZF3 | |
| SCHEMBL29546738 | 0.83 | CRBN (0.53) | IKZF2CRBNIKZF1DDB1IKZF3 | |
| SCHEMBL31727485 | 0.83 | CRBN (0.50) | CRBNIKZF1DDB1IKZF3CSNK1A1 | |
| SCHEMBL24816874 | 0.83 | CRBN (0.50) | CRBNIKZF1DDB1IKZF3CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268229-A1 | PROTEIN INHIBITOR OR DEGRADING AGENT, PHARMACEUTICAL COMPOSITION CONTAINING SAME AND PHARMACEUTICAL USE | 和径医药科技（上海）有限公司 | 2022-12-29 | — | — | WO | disclosed |