Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 20/20 | 0.58 |
| ▸ | CRBN | Q96SW2 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24820984 | 0.86 | DDB1 (0.63) | DDB1CRBN | |
| SCHEMBL22526400 | 0.78 | DDB1 (0.70) | DDB1CRBN | |
| SCHEMBL20845725 | 0.78 | DDB1 (0.69) | DDB1CRBN | |
| SCHEMBL21106895 | 0.77 | CRBN (0.67) | DDB1CRBN | |
| SCHEMBL22525243 | 0.77 | CRBN (0.67) | DDB1CRBN | |
| SCHEMBL21106273 | 0.77 | CRBN (0.67) | DDB1CRBN | |
| SCHEMBL21106897 | 0.77 | CRBN (0.67) | DDB1CRBN | |
| SCHEMBL25834828 | 0.76 | CRBN (0.59) | DDB1CRBN | |
| SCHEMBL24204781 | 0.75 | CRBN (0.58) | DDB1CRBN | |
| SCHEMBL21106894 | 0.74 | DDB1 (0.67) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022271727-A1 | DEGRADER COMPOUNDS AND USES THEREOF | CALICO LIFE SCIENCES LLC (US) | 2022-12-29 | — | — | WO | disclosed |