SCHEMBL24819870

SCHEMBL24819870

CCN(Cc1cc(C(F)(F)F)c2oc(-c3cc(-c4ccc(F)cc4-c4nncn4C)cc(C4CC4)n3)nc2c1)CC1(C#N)CCCC1

nearest known ligand 0.42

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30152591 1.00 CBLB (0.42) CBLB
SCHEMBL24819881 0.89 CBLB (0.34) CBLB
SCHEMBL30152845 0.89 CBLB (0.34) CBLB
SCHEMBL30152924 0.88 CBLB (0.50) CBLB
SCHEMBL24818583 0.88 CBLB (0.50) CBLB
SCHEMBL24821930 0.83 CBLB (0.39) CBLB
SCHEMBL24820120 0.82 CBLB (0.37) CBLB
SCHEMBL30152968 0.80 CBLB (0.49) CBLB
SCHEMBL24820035 0.80 CBLB (0.49) CBLB
SCHEMBL24818957 0.79 CBLB (0.38) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022272248-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2022-12-29 — — WO disclosed
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