SCHEMBL24820035

SCHEMBL24820035

Cn1cnnc1-c1cc(F)ccc1-c1cc(-c2nc3cc(CNCC4(O)CCC4)cc(C(F)(F)F)c3o2)nc(C2CC2)c1

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30152968 1.00 CBLB (0.49) CBLB
SCHEMBL30153059 0.92 CBLB (0.42) CBLB
SCHEMBL30152615 0.92 CBLB (0.42) CBLB
SCHEMBL24819000 0.92 CBLB (0.42) CBLB
SCHEMBL24821978 0.92 CBLB (0.42) CBLB
SCHEMBL24818995 0.91 CBLB (0.44) CBLB
SCHEMBL30152658 0.91 CBLB (0.44) CBLB
SCHEMBL24818583 0.90 CBLB (0.50) CBLB
SCHEMBL30152924 0.90 CBLB (0.50) CBLB
SCHEMBL24818681 0.88 CBLB (0.41) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117858865-A CBL-B modulators and uses thereof 林伯士克莱奥公司 2024-04-09 — — CN disclosed
WO-2022272248-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2022-12-29 — — WO disclosed
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