Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 9/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | UTRN | P46939 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152902 | 1.00 | VSIR (0.41) | VSIRPDCD1CD274SMN1; SMN2S1PR1 | |
| SCHEMBL30153157 | 0.89 | VSIR (0.42) | VSIRPDCD1CD274HPGD | |
| SCHEMBL24818711 | 0.89 | VSIR (0.42) | VSIRPDCD1CD274NPC1MAPT | |
| SCHEMBL24818963 | 0.89 | VSIR (0.42) | VSIRPDCD1CD274HPGD | |
| SCHEMBL24819890 | 0.87 | VSIR (0.41) | VSIRPDCD1CD274S1PR1S1PR3 | |
| SCHEMBL30152704 | 0.86 | CBLB (0.36) | VSIRPDCD1CD274S1PR1S1PR3 | |
| SCHEMBL24821816 | 0.86 | CBLB (0.36) | VSIRPDCD1CD274S1PR1S1PR3 | |
| SCHEMBL24819847 | 0.86 | KDM4E (0.41) | VSIRPDCD1CD274SMN1; SMN2S1PR1 | |
| SCHEMBL24819865 | 0.86 | VSIR (0.43) | VSIRPDCD1CD274SMN1; SMN2KDM4E | |
| SCHEMBL30152789 | 0.86 | VSIR (0.43) | VSIRPDCD1CD274SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |