SCHEMBL24818995

SCHEMBL24818995

Cn1cnnc1-c1cc(F)ccc1-c1cc(-c2nc3cc(CNCC4(O)CCC4)cc(C(F)(F)F)c3o2)cc(C2CC2)c1

nearest known ligand 0.44

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30152658 1.00 CBLB (0.44) CBLB
SCHEMBL24820035 0.91 CBLB (0.49) CBLB
SCHEMBL30152968 0.91 CBLB (0.49) CBLB
SCHEMBL24818681 0.90 CBLB (0.41) CBLB
SCHEMBL24818764 0.90 CBLB (0.40) CBLB
SCHEMBL30152848 0.90 CBLB (0.40) CBLB
SCHEMBL24819853 0.89 CBLB (0.40) CBLB
SCHEMBL30153102 0.88 CBLB (0.38) CBLB
SCHEMBL24819035 0.88 CBLB (0.38) CBLB
SCHEMBL24819850 0.88 VSIR (0.39) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022272248-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2022-12-29 — — WO disclosed
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