Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750862 | 0.77 | KDM4E (0.55) | MAPTALDH1A1LMNAGAAKDM4E | |
| SCHEMBL2807784 | 0.76 | MAPT (0.56) | MAPTALDH1A1LMNAGAAKDM4E | |
| SCHEMBL31582154 | 0.75 | ALDH1A1 (0.49) | MAPTALDH1A1LMNAGAAKDM4E | |
| SCHEMBL10487792 | 0.74 | MAPT (0.54) | MAPTALDH1A1LMNAGAAKDM4E | |
| SCHEMBL8427360 | 0.72 | TPMT (0.48) | MAPTALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL6667910 | 0.72 | MAPT (0.62) | MAPTALDH1A1LMNAGAAKDM4E | |
| SCHEMBL11336062 | 0.71 | MEN1 (0.47) | MAPTALDH1A1LMNAGAAKDM4E | |
| SCHEMBL14203260 | 0.68 | KMT2A (0.48) | MAPTALDH1A1LMNAGAAKDM4E | |
| SCHEMBL9417798 | 0.68 | MAPT (0.55) | MAPTALDH1A1LMNAGAAKMT2A | |
| SCHEMBL27940443 | 0.68 | KDM4E (0.71) | MAPTALDH1A1LMNAGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |