Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.49 |
| ▸ | LAP3 | P28838 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.38 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16286566 | 1.00 | FOLH1 (0.49) | FOLH1LAP3TSHRRNPEPSLC7A5 | |
| SCHEMBL19301334 | 0.84 | FOLH1 (0.50) | FOLH1LAP3RNPEPSLC7A5ALDH1A1 | |
| SCHEMBL6904512 | 0.84 | TSHR (0.46) | FOLH1LAP3TSHRRNPEPSLC7A5 | |
| SCHEMBL9421350 | 0.81 | TSHR (0.39) | FOLH1LAP3TSHRCHRM2CHRM4 | |
| SCHEMBL5349776 | 0.80 | TSHR (0.42) | FOLH1LAP3TSHRRNPEPSLC7A5 | |
| SCHEMBL5349785 | 0.80 | TSHR (0.42) | FOLH1LAP3TSHRRNPEPSLC7A5 | |
| SCHEMBL8613929 | 0.80 | FOLH1 (0.47) | FOLH1LAP3RNPEPSLC7A5ALDH1A1 | |
| SCHEMBL28022777 | 0.80 | TSHR (0.42) | FOLH1LAP3TSHRCHRM2CHRM4 | |
| SCHEMBL15945449 | 0.78 | TSHR (0.41) | FOLH1TSHRALDH1A1CHRM2CHRM4 | |
| SCHEMBL28022769 | 0.78 | FOLH1 (0.46) | FOLH1LAP3RNPEPSLC7A5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104755510-A | Ziegler-Natta catalyst systems comprising a 1,2-phenylenedioate as internal donor and process for preparing the same | INDIAN OIL CORP LTD | 2015-07-01 | — | — | CN | claimed |
| CN-104755510-B | Ziegler natta catalyst system of internal donor and preparation method thereof is used as comprising 1,2 phenylene diester | 印度石油有限公司 | 2017-11-07 | — | — | CN | disclosed |
| EP-3116031-A1 | ORGANIC THIN FILM TRANSISTOR AND METHOD FOR MANUFACTURING SAME | Fujifilm Corporation (JP) | 2017-01-11 | — | — | EP | disclosed |
| CN-104755510-A | Ziegler-Natta catalyst systems comprising a 1,2-phenylenedioate as internal donor and process for preparing the same | INDIAN OIL CORP LTD | 2015-07-01 | — | — | CN | disclosed |
| EP-1735332-B1 | AZACYCLOSTEROID HISTAMINE-3 RECEPTOR LIGANDS | ABBOTT LAB (US) | 2011-10-19 | — | — | EP | disclosed |
| US-20080113982-A1 | AZACYCLOSTEROID HISTAMINE-3 RECEPTOR LIGANDS | ZHAO CHEN | 2008-05-15 | — | — | US | disclosed |
| US-7345034-B2 | Azacyclosteroid histamine-3 receptor ligands | ABBOTT LABORATORIES (US) | 2008-03-18 | — | — | US | disclosed |
| EP-1735332-A1 | AZACYCLOSTEROID HISTAMINE-3 RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2006-12-27 | — | — | EP | disclosed |
| US-20050245495-A1 | Azacyclosteroid histamine-3 receptor ligands | ABBOTT LABORATORIES | 2005-11-03 | — | — | US | disclosed |
| WO-2005100377-A1 | AZACYCLOSTEROID HISTAMINE-3 RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2005-10-27 | — | — | WO | disclosed |
| US-20050227953-A1 | Azacyclosteroid histamine-3 receptor ligands | ABBVIE INC. | 2005-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050227953-A1 | Azacyclosteroid histamine-3 receptor ligands | HRH4, HRH3, HRH2 | FOLH1 1509/4885LAP3 1582/4885TSHR 304/4885 |
| US-20050245495-A1 | Azacyclosteroid histamine-3 receptor ligands | HRH4, HRH3, HRH2 | FOLH1 1509/4885LAP3 1582/4885TSHR 304/4885 |
| US-20080113982-A1 | AZACYCLOSTEROID HISTAMINE-3 RECEPTOR LIGANDS | HRH4, HRH3, HRH2 | FOLH1 1509/4885LAP3 1582/4885TSHR 304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.