Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 9/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.34 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | IL1B | P01584 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24820339 | 1.00 | TRPV3 (0.39) | TRPV3CD274PDCD1LG2PDCD1PDE3B | |
| SCHEMBL24820331 | 1.00 | TRPV3 (0.39) | TRPV3CD274PDCD1LG2PDCD1PDE3B | |
| SCHEMBL24820333 | 1.00 | TRPV3 (0.39) | TRPV3CD274PDCD1LG2PDCD1PDE3B | |
| SCHEMBL24819817 | 0.79 | TRPV3 (0.39) | TRPV3CD274PDCD1LG2PDCD1PDE3B | |
| SCHEMBL24819811 | 0.79 | TRPV3 (0.39) | TRPV3CD274PDCD1LG2PDCD1PDE3B | |
| SCHEMBL24819795 | 0.79 | TRPV3 (0.39) | TRPV3CD274PDCD1LG2PDCD1PDE3B | |
| SCHEMBL24819802 | 0.79 | TRPV3 (0.39) | TRPV3CD274PDCD1LG2PDCD1PDE3B | |
| SCHEMBL24819781 | 0.79 | TRPV3 (0.39) | TRPV3CD274PDCD1LG2PDCD1PDE3B | |
| SCHEMBL24818520 | 0.77 | CD274 (0.41) | TRPV3CD274PDCD1LG2PDCD1LTA4H | |
| SCHEMBL24820330 | 0.76 | MAPT (0.37) | ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |