SCHEMBL24820447

SCHEMBL24820447

CCN(CC(C)C)CC1(C#N)CCCC1

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.42
MAPK1 P28482 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27284381 0.85 SLC6A2 (0.33)
SCHEMBL27284377 0.79 CYP1A2 (0.36) CYP1A2MAPK1
SCHEMBL27257058 0.70 ALDH1A1 (0.34) CYP1A2MAPK1
SCHEMBL11373090 0.67 ALDH1A1 (0.36)
SCHEMBL2292115 0.66
SCHEMBL27281332 0.66
SCHEMBL19118037 0.65 KDM1A (0.30) CYP1A2MAPK1
SCHEMBL806005 0.65
SCHEMBL35704 0.65 CYP1A2 (0.46) CYP1A2MAPK1
SCHEMBL2567754 0.64 CYP1A2 (0.40) CYP1A2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024081311-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2024-04-18 WO disclosed
WO-2022272248-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2022-12-29 WO disclosed