Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24820449 | 1.00 | CETP (0.37) | CETPLMNAPKMSIGMAR1 | |
| SCHEMBL24820468 | 0.86 | CETP (0.31) | CETP | |
| SCHEMBL25178946 | 0.76 | CETP (0.40) | CETPPKM | |
| SCHEMBL7229021 | 0.73 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL2616358 | 0.72 | — | — | |
| SCHEMBL11989936 | 0.72 | — | — | |
| SCHEMBL9945809 | 0.72 | — | — | |
| SCHEMBL1446074 | 0.72 | SIGMAR1 (0.35) | SIGMAR1 | |
| SCHEMBL6230212 | 0.71 | CETP (0.56) | CETPLMNAPKM | |
| SCHEMBL1230110 | 0.70 | TSHR (0.40) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |