Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTRN | P46939 | 3/20 | 0.35 |
| ▸ | VSIR | Q9H7M9 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153060 | 1.00 | UTRN (0.35) | UTRNVSIRMAPTNPC1RAB9A | |
| SCHEMBL24818786 | 0.89 | UTRN (0.38) | UTRNVSIRMAPTNPC1RAB9A | |
| SCHEMBL30153038 | 0.89 | UTRN (0.38) | UTRNVSIRMAPTNPC1RAB9A | |
| SCHEMBL24818801 | 0.87 | UTRN (0.38) | UTRNMAPTNPC1RAB9AKDM4E | |
| SCHEMBL30153073 | 0.86 | VSIR (0.38) | UTRNVSIRNPC1RAB9AHPGD | |
| SCHEMBL24818919 | 0.86 | VSIR (0.38) | UTRNVSIRNPC1RAB9AHPGD | |
| SCHEMBL30152631 | 0.85 | VSIR (0.41) | UTRNVSIRNPC1RAB9AHPGD | |
| SCHEMBL24819054 | 0.85 | VSIR (0.41) | UTRNVSIRNPC1RAB9AHPGD | |
| SCHEMBL24820770 | 0.84 | VSIR (0.38) | UTRNVSIRMAPTNPC1RAB9A | |
| SCHEMBL30152980 | 0.84 | VSIR (0.38) | UTRNVSIRMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |