Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | VSIR | Q9H7M9 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153133 | 1.00 | KCNH2 (0.35) | KCNH2KDM4EALDH1A1VSIRCNR1 | |
| SCHEMBL24820547 | 0.93 | VSIR (0.33) | KCNH2VSIRPDCD1CD274 | |
| SCHEMBL30153066 | 0.93 | VSIR (0.33) | KCNH2VSIRPDCD1CD274 | |
| SCHEMBL24818932 | 0.93 | KDM4E (0.40) | KCNH2KDM4EALDH1A1VSIRCYP2D6 | |
| SCHEMBL30152806 | 0.92 | VSIR (0.32) | VSIRPDCD1CD274 | |
| SCHEMBL24821940 | 0.92 | VSIR (0.32) | VSIRPDCD1CD274 | |
| SCHEMBL30152798 | 0.91 | CBLB (0.33) | VSIR | |
| SCHEMBL24820059 | 0.91 | CBLB (0.33) | VSIR | |
| SCHEMBL24819863 | 0.89 | CD274 (0.39) | KCNH2VSIRPDCD1CD274 | |
| SCHEMBL24820787 | 0.88 | VSIR (0.31) | VSIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |