Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 17/20 | 0.53 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10567915 | 0.79 | SORD (0.83) | SORD | |
| SCHEMBL10565986 | 0.79 | SORD (0.57) | SORDCXCR4MAP4K4 | |
| SCHEMBL15121155 | 0.79 | SORD (0.57) | SORDCXCR4MAP4K4 | |
| SCHEMBL10566742 | 0.77 | SORD (0.86) | SORD | |
| SCHEMBL20098856 | 0.77 | SORD (0.59) | SORDCXCR4 | |
| SCHEMBL14554003 | 0.76 | SORD (0.54) | SORDCXCR4 | |
| Hydrochloric Acid SCHEMBL10567593 | 0.76 | SORD (0.57) | SORDCXCR4 | |
| SCHEMBL14552437 | 0.75 | SORD (0.53) | SORDCXCR4 | |
| SCHEMBL10564194 | 0.75 | SORD (0.53) | SORDCXCR4 | |
| SCHEMBL30635502 | 0.74 | GBA1 (0.55) | SORDCXCR4GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376488-A1 | 2- (PIPERIDIN-1-YL) -4-HETEROCYCLYL-THIAZOLE-5-CARBOXYLIC ACID DERIVATIVES AGAINST BACTERIAL INFECTIONS | AstraZeneca AB (SE) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010067123-A1 | 2- (PIPERIDIN-1-YL) -4-HETEROCYCLYL-THIAZOLE-5-CARBOXYLIC ACID DERIVATIVES AGAINST BACTERIAL INFECTIONS | ASTRAZENECA AB (SE) | 2010-06-17 | — | — | WO | disclosed |