SORD — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL4263702	0.52	18/20
SCHEMBL2482087	0.53	17/20
SCHEMBL2616799	0.51	15/20
SCHEMBL509749	0.56	13/20
SCHEMBL1588709	0.45	12/20
SCHEMBL509308	0.52	11/20
SCHEMBL4158876	0.50	8/20
SCHEMBL1427771	0.43	8/20
SCHEMBL3294901	0.50	7/20
SCHEMBL509736	0.61	6/20
SCHEMBL2074918	0.42	6/20
SCHEMBL3536631	0.40	6/20
SCHEMBL3536634	0.40	6/20
SCHEMBL3640716	0.48	5/20
SCHEMBL509692	0.59	4/20
SCHEMBL3852629	0.47	4/20
SCHEMBL860012	0.43	4/20
Hydrochloric Acid (SCHEMBL3975778)	0.60	3/20
SCHEMBL510365	0.58	3/20
SCHEMBL1089215	0.57	3/20

Clinical trials — most relevant to SORD by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Efficacy and Safety of Rheosorbilact® Solution for Infusion, in a Complex Therapy of Burns	PHASE4	COMPLETED
Efficacy and Safety of Rheosorbilact® Solution for Infusion, in a Complex Therapy of Peritonitis	PHASE4	COMPLETED
Efficacy and Safety of Rheosorbilact® Solution for Infusion, in a Complex Therapy of Sepsis.	PHASE4	COMPLETED
Lactate Metabolism Study in HIV Infected Persons	PHASE4	COMPLETED
A Phase IV, Open Label, 4-period Cross-over Study to Investigate a Drug Interaction Between Lamivudine and Sorbitol Oral Solutions in Healthy Volunteers	PHASE4	COMPLETED
Nitrite Infusion in High Risk Patients Undergoing Cardiopulmonary Bypass	PHASE3	WITHDRAWN
Metabolic Cofactor Supplementation in Alzheimer's Disease (AD) and Parkinson's Disease (PD) Patients	PHASE2	COMPLETED
Acetylcarnitine and Insulin Sensitivity	PHASE2	COMPLETED
Hydroxyproline Influence on Oxalate Metabolism	PHASE1/PHASE2	COMPLETED
First-line Irinotecan, Lederfolin and 5FU (FOLFIRI) and Bevacizumab in Patients With Advanced Colorectal Cancer	PHASE2	COMPLETED
MT2013-31: Allo HCT for Metabolic Disorders and Severe Osteopetrosis	PHASE2	ACTIVE_NOT_RECRUITING
The Effect of Triheptanoin on Fatty Acid Oxidation and Exercise Tolerance in Patients With Glycogenoses	PHASE2	COMPLETED
Non-oxidative Metabolite Profiles After Increasing Doses of Ethanol	PHASE1	COMPLETED
UCB Transplant of Inherited Metabolic Diseases With Administration of Intrathecal UCB Derived Oligodendrocyte-Like Cells	PHASE1	RECRUITING
18F-FDS PET/CT in Healthy Volunteers and Patients With Suspected Infection	EARLY_PHASE1	UNKNOWN
Safety and Immunogenicity Evaluation of the Recombinant Flagellin Protein Adjuvant	EARLY_PHASE1	NOT_YET_RECRUITING
Washed Microbiota Transplantation for Food Intolerance	nan	RECRUITING
McArdle Disease Treatment by Ketogenic Diet	nan	COMPLETED
Natural History Study of FDXR Mutation-related Mitochondriopathy	nan	COMPLETED
MyRareDiet A Novel Diet Tracking Tool	nan	NOT_YET_RECRUITING
Potential Synergistic Effect of Combined Blood Flow Restriction Training and Betaine Supplementation on Skeletal Muscle	nan	COMPLETED
Effect of Acute Fructose Load in Human	nan	COMPLETED
A Non-interventional Study of REVLIMID® (Lenalidomide) Treatment of IPSS Low- or Intermediate-1-risk Myelodysplastic Syndromes Associated With a Deletion 5q or Refractory/Relapsed Mantle Cell Lymphoma in Korea	nan	COMPLETED
Tolerability and Efficacy of L-Serine in Patients With GRIN-related Encephalopathy	nan	UNKNOWN
Sucrase-isomaltase Deficiency as a Cause of Irritable Bowel Syndrome	nan	NOT_YET_RECRUITING
Chronic Sucrose Intake, Markers of Health and Biomarker Identification	nan	UNKNOWN
A Relative Bioavailability Study of Valacyclovir Hydrochloride Tablets 1gm Under Fed Condition	nan	COMPLETED
Malaria Surveillance in Rakai, Uganda	nan	COMPLETED
Pharmacogenetic Determinants Of Treatment Response In Children	nan	RECRUITING
Red Blood Cell Exchange Transfusion as a Novel Treatment for GLUT1 Deficiency Syndrome	nan	SUSPENDED

Related proteins — ESM-2 sequence neighbours (a SORD binder may also engage these)

Protein	Name	Similarity
Q58D31	—	1.000	Q58D31 →
Q5R5F3	—	1.000	Q5R5F3 →
Q4R639	—	1.000	Q4R639 →
P07846	—	0.997	P07846 →
P27867	—	0.996	P27867 →
Q64442	—	0.995	Q64442 →
P0DMQ6	—	0.991	P0DMQ6 →
C5FTT1	—	0.988	C5FTT1 →
Q7SI09	—	0.985	Q7SI09 →
ADH1C	Alcohol dehydrogenase 1C	0.984	landscape →
P93629	—	0.984	P93629 →
P36624	—	0.983	P36624 →
O19053	—	0.983	O19053 →
P19854	—	0.983	P19854 →
P00328	—	0.983	P00328 →
P80360	—	0.983	P80360 →
P86885	—	0.982	P86885 →
Q64415	—	0.982	Q64415 →
ADH1A	Alcohol dehydrogenase 1A	0.982	landscape →
P81601	—	0.982	P81601 →
P28474	—	0.982	P28474 →
Q3ZC42	—	0.982	Q3ZC42 →
Q5GN51	—	0.982	Q5GN51 →
O97959	—	0.982	O97959 →
P80338	—	0.981	P80338 →
Q5R1W2	—	0.981	Q5R1W2 →
P79896	—	0.981	P79896 →
P14139	—	0.981	P14139 →
Q5RBP7	—	0.981	Q5RBP7 →
Q9FJ95	—	0.981	Q9FJ95 →