Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.77 |
| ▸ | MEN1 | O00255 | 5/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.77 |
| ▸ | NPC1 | O15118 | 1/20 | 0.77 |
| ▸ | RAB9A | P51151 | 1/20 | 0.77 |
| ▸ | CA12 | O43570 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.63 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | PPARA | Q07869 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16082991 | 0.91 | ALDH1A1 (0.83) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL5860896 | 0.85 | ALDH1A1 (0.73) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL26167952 | 0.85 | KMT2A (0.55) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL7285179 | 0.85 | ALDH1A1 (0.73) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL7879611 | 0.83 | MEN1 (0.66) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL3942498 | 0.83 | MEN1 (0.71) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL7873804 | 0.81 | MEN1 (0.68) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL25894323 | 0.80 | KMT2A (0.59) | KMT2AMEN1ALDH1A1HPGDPOLB | |
| SCHEMBL13436807 | 0.80 | HPGD (0.67) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL296162 | 0.80 | TAAR1 (0.60) | KMT2AMEN1ALDH1A1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968347-B1 | MODULATORS OF THE EIF2ALPHA PATHWAY | UNIV CALIFORNIA (US) | 2023-08-02 | — | — | EP | disclosed |
| WO-2022268066-A1 | PROTEIN DEGRADATION AGENT | 苏州开拓药业股份有限公司 | 2022-12-29 | — | — | WO | disclosed |