Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 14/20 | 0.56 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.56 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.56 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.53 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.49 |
| ▸ | IKZF2 | Q9UKS7 | 4/20 | 0.47 |
| ▸ | WIZ | O95785 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21069987 | 0.92 | CRBN (0.66) | CRBNDDB1GSPT1IKZF3CYP2C19 | |
| SCHEMBL24078806 | 0.91 | CRBN (0.67) | CRBNDDB1GSPT1IKZF3CYP2C19 | |
| SCHEMBL30213344 | 0.91 | CRBN (0.67) | CRBNDDB1GSPT1IKZF3CYP2C19 | |
| SCHEMBL30400720 | 0.89 | CRBN (0.55) | CRBNDDB1GSPT1IKZF3CYP2C19 | |
| SCHEMBL30400916 | 0.89 | CRBN (0.55) | CRBNDDB1GSPT1IKZF3CYP2C19 | |
| SCHEMBL29368466 | 0.87 | CRBN (0.60) | CRBNDDB1GSPT1IKZF3CYP2C19 | |
| SCHEMBL31389719 | 0.86 | CRBN (0.57) | CRBNDDB1GSPT1IKZF3CYP2C19 | |
| SCHEMBL25473073 | 0.86 | CRBN (0.59) | CRBNDDB1GSPT1IKZF3CYP2C19 | |
| SCHEMBL4450381 | 0.86 | CRBN (0.55) | CRBNDDB1GSPT1IKZF3CYP2C19 | |
| SCHEMBL26147411 | 0.86 | CRBN (0.61) | CRBNDDB1GSPT1IKZF3CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268066-A1 | PROTEIN DEGRADATION AGENT | 苏州开拓药业股份有限公司 | 2022-12-29 | — | — | WO | disclosed |