Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | SOX18 | P35713 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9127039 | 0.89 | SIGMAR1 (0.56) | HTR2AHTR2CHTR2BCYP1A2CYP2A6 | |
| SCHEMBL9126634 | 0.88 | SIGMAR1 (0.54) | HTR2AHTR2CHTR2BCYP1A2CYP2A6 | |
| SCHEMBL9128987 | 0.86 | SIGMAR1 (0.53) | HTR2AHTR2CHTR2BCYP1A2CYP2A6 | |
| SCHEMBL9127853 | 0.86 | SIGMAR1 (0.53) | HTR2AHTR2CHTR2BCYP1A2CYP2A6 | |
| SCHEMBL26846103 | 0.85 | HTR2A (0.56) | HTR2AHTR2CHTR2BCYP1A2CYP2A6 | |
| SCHEMBL9125921 | 0.84 | TYR (0.54) | HTR2ACYP1A2SIGMAR1ADRB2GRIN2D | |
| SCHEMBL8422662 | 0.82 | CYP1A2 (0.53) | HTR2AHTR2CHTR2BCYP1A2CYP2A6 | |
| SCHEMBL9294768 | 0.82 | HTR2A (0.46) | HTR2AHTR2CHTR2BCYP1A2CYP2A6 | |
| SCHEMBL24851230 | 0.81 | HTR2A (0.53) | HTR2AHTR2CHTR2BCYP1A2CYP2A6 | |
| SCHEMBL7900491 | 0.81 | HTR2A (0.53) | HTR2AHTR2CHTR2BCYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8717565-B2 | Optically active functional fluid markers | THE LUBRIZOL CORPORATION (US) | 2014-05-06 | — | — | US | disclosed |
| EP-1814848-B9 | 2,3,4-SUBSTITUTED-CYCLOPENTANONES AS THERAPEUTIC AGENTS | ALLERGAN INC (US) | 2011-12-21 | — | — | EP | disclosed |
| EP-2376894-A1 | OPTICALLY ACTIVE FUNCTIONAL FLUID MARKERS | The Lubrizol Corporation (US) | 2011-10-19 | — | — | EP | disclosed |
| EP-2373977-A1 | OPTICALLY ACTIVE FUNCTIONAL FLUID MARKERS | The Lubrizol Corporation (US) | 2011-10-12 | — | — | EP | disclosed |
| EP-1814848-B1 | 2,3,4-SUBSTITUTED-CYCLOPENTANONES AS THERAPEUTIC AGENTS | ALLERGAN INC (US) | 2010-07-28 | — | — | EP | disclosed |
| WO-2010077753-A1 | OPTICALLY ACTIVE FUNCTIONAL FLUID MARKERS | THE LUBRIZOL CORPORATION (US) | 2010-07-08 | — | — | WO | disclosed |
| WO-2010077754-A1 | OPTICALLY ACTIVE FUNCTIONAL FLUID MARKERS | THE LUBRIZOL CORPORATION (US) | 2010-07-08 | — | — | WO | disclosed |
| US-7183324-B2 | 2,3,4-substituted cyclopentanones as therapeutic agents | ALLERGAN, INC. (US) | 2007-02-27 | — | — | US | disclosed |
| US-7183324-B2 | 2,3,4-substituted cyclopentanones as therapeutic agents | ALLERGAN, INC. (US) | 2007-02-27 | — | — | US | disclosed |
| US-5422038-A | Ferroelectric liquid crystal material with sufficient spontaneous polarization, high speed response capability, wide temperature range | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-06-06 | — | — | US | disclosed |
| EP-0416946-B1 | Optically active naphthalene derivative, process for preparation thereof, liquid crystal composition containing the same as effective component, and liquid crystal element using the same | SUMITOMO CHEMICAL CO (JP) | 1994-11-09 | — | — | EP | disclosed |
| EP-0416946-A2 | Optically active naphthalene derivative, process for preparation thereof, liquid crystal composition containing the same as effective component, and liquid crystal element using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-03-13 | — | — | EP | disclosed |