SCHEMBL2482286

SCHEMBL2482286

CCCCc1cc(Sc2cc(CCCC)c(O)cc2C)c(C)cc1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.49
MAPK1 P28482 4/20 0.44
TP53 P04637 4/20 0.44
CYP3A4 P08684 3/20 0.44
ALOX15 P16050 3/20 0.44
ALDH1A1 P00352 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
TSHR P16473 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
HIF1A Q16665 1/20 0.44
HTT P42858 3/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
HPGD P15428 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43
MAPT P10636 3/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
ALOX5 P09917 1/20 0.42
HMGCR P04035 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31121127 1.00 TYR (0.49) TYRMAPK1TP53CYP3A4ALOX15
SCHEMBL9744765 0.93 ALOX5 (0.51) TYRMAPK1TP53CYP3A4ALOX15
SCHEMBL2479859 0.93 ALOX5 (0.51) TYRMAPK1TP53CYP3A4ALOX15
SCHEMBL9746117 0.93 ALOX5 (0.51) TYRMAPK1TP53CYP3A4ALOX15
SCHEMBL2484244 0.93 ALOX5 (0.51) TYRMAPK1TP53CYP3A4ALOX15
SCHEMBL14303453 0.92 MAPK1 (0.42) TYRMAPK1TP53CYP3A4ALOX15
SCHEMBL2480931 0.89 TP53 (0.47) TYRMAPK1TP53CYP3A4ALOX15
SCHEMBL1755478 0.86 TYR (0.38) TYRMAPK1TP53CYP3A4ALOX15
SCHEMBL12457005 0.85 TYR (0.40) TYRMAPK1TP53CYP3A4ALOX15
SCHEMBL12166722 0.83 TYR (0.57) TYRMAPK1TP53CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3885425-B1 GREASE COMPOSITION FOR TAPERED ROLLER BEARING KYODO YUSHI (JP) 2023-06-28 EP claimed
WO-2007136565-A1 STABILIZER COMPOSITIONS CYTEC TECHNOLOGY CORP. (US) 2007-11-29 WO claimed
EP-0752445-B1 Rubber compositions for tire tread BRIDGESTONE CORP (JP) 2002-08-21 EP claimed
US-6187843-B1 BLEND OF RUBBER WITH NITROGEN-CONTAINING COMPOUND BRIDGESTONE CORPORATION (JP) 2001-02-13 US claimed
EP-0752445-A2 Rubber compositions for tire tread Bridgestone Corporation (JP) 1997-01-08 EP claimed
EP-0230597-B1 METHOD FOR INHIBITING POLYMERIZATION OF MALEIMIDES Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) 1992-04-08 EP claimed
EP-0230597-A2 Method for inhibiting polymerization of maleimides Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) 1987-08-05 EP claimed
JP-11329082-A None JP disclosed
JP-59014991-A None JP disclosed
EP-4711410-A1 COMPOSITION WITH BALANCE OF DISSIPATION FACTOR AND ADDITIVE ACCEPTANCE Dow Global Technologies LLC (US) 2026-03-18 EP disclosed
EP-3541869-B1 COMPOSITION WITH BALANCE OF DISSIPATION FACTOR AND ADDITIVE ACCEPTANCE DOW GLOBAL TECHNOLOGIES LLC (US) 2025-11-05 EP disclosed
US-11667735-B2 Polyolefin composition DOW GLOBAL TECHNOLOGIES LLC (US) 2023-06-06 US disclosed
US-20220098337-A1 POLYOLEFIN COMPOSITION DOW GLOBAL TECHNOLOGIES LLC (US) 2022-03-31 US disclosed
JP-S5914991-A HEAT SENSITIVE RECORDING MATERIAL RICOH CO LTD 1984-01-25 JP disclosed
US-4410648-A CYCLIC ANHYDRIDE OR IMIDE, INORGANIC POWDER, POLYUNSATURATED MONOMER DAINICHI-NIPPON CABLES, LTD. (JP) 1983-10-18 US disclosed
EP-0086842-A1 METHOD FOR BONDING POLYOLEFIN ARTICLES DAINICHI-NIPPON CABLES, LTD. (JP) 1983-08-31 EP disclosed
EP-0019578-B1 PIPERIDINE DERIVATIVES, PROCESS FOR PREPARING THEM AND POLYMER COMPOSITIONS CONTAINING THEM Chimosa Chimica Organica S.p.A. (IT) 1983-03-30 EP disclosed
EP-0019578-A1 Piperidine derivatives, process for preparing them and polymer compositions containing them Chimosa Chimica Organica S.p.A. (IT) 1980-11-26 EP disclosed
US-4148747-A FOR POLYMERS RAYCHEM CORPORATION (US) 1979-04-10 US disclosed
US-4009147-A POLYMERIC BISPHENOLS RAYCHEM CORPORATION (US) 1977-02-22 US disclosed