Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10412153 | 0.76 | TP53 (0.41) | KDM4EALDH1A1HSD17B10CYP1A2MEN1 | |
| SCHEMBL8040679 | 0.73 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL3220230 | 0.72 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10HTR2A | |
| SCHEMBL17127058 | 0.71 | KDM4E (0.41) | KDM4EALDH1A1MEN1HCRTR1KMT2A | |
| SCHEMBL21983716 | 0.70 | CYP2A6 (0.39) | KDM4EALDH1A1HTR2AHTR2CCYP1A2 | |
| SCHEMBL10284105 | 0.69 | HTR2C (0.41) | KDM4EALDH1A1HPGDHSD17B10HTR2A | |
| SCHEMBL19506933 | 0.69 | PRMT5 (0.45) | KDM4EALDH1A1HPGDHSD17B10HTR2A | |
| SCHEMBL12580665 | 0.68 | PRMT5 (0.44) | KDM4EALDH1A1HPGDHSD17B10HTR2A | |
| SCHEMBL13343094 | 0.67 | ATM (0.37) | KDM4EALDH1A1 | |
| SCHEMBL4054875 | 0.67 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272060-A1 | EP2 ANTAGONIST COMPOUNDS | RESERVOIR NEUROSCIENCE, INC. (US) | 2022-12-29 | — | — | WO | disclosed |