Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24198356 | 0.72 | TP53 (0.38) | — | |
| SCHEMBL256368 | 0.71 | ELANE (0.42) | ELANECCNB2CDK1CCNB1CDK5 | |
| SCHEMBL31637708 | 0.70 | ELANE (0.44) | ELANECCNB2CDK1CCNB1CDK5 | |
| SCHEMBL2280415 | 0.67 | ELANE (0.42) | ELANECCNB2CDK1CCNB1CDK5 | |
| SCHEMBL18938891 | 0.67 | ELANE (0.42) | ELANECCNB2CDK1CCNB1CDK5 | |
| SCHEMBL18237765 | 0.67 | ELANE (0.39) | ELANECCNB2CDK1CCNB1CDK5 | |
| SCHEMBL12844053 | 0.67 | ELANE (0.39) | ELANECCNB2CDK1CCNB1CDK5 | |
| SCHEMBL12775635 | 0.67 | ELANE (0.42) | ELANECCNB2CDK1CCNB1CDK5 | |
| SCHEMBL24670234 | 0.64 | MET (0.47) | ELANEMET | |
| SCHEMBL22388588 | 0.64 | ELANE (0.37) | ELANECCNB2CDK1CCNB1CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272060-A1 | EP2 ANTAGONIST COMPOUNDS | RESERVOIR NEUROSCIENCE, INC. (US) | 2022-12-29 | — | — | WO | disclosed |