Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24775869 | 0.84 | AOC3 (0.33) | AOC3CHRM2CHRM3TYK2BRD4 | |
| SCHEMBL24823950 | 0.82 | CHRM2 (0.35) | CHRM2CHRM3 | |
| SCHEMBL24823461 | 0.80 | CYP11B1 (0.34) | — | |
| SCHEMBL24823659 | 0.78 | AOC3 (0.32) | AOC3CHRM2CHRM3TYK2BRD4 | |
| SCHEMBL30079527 | 0.73 | AOC3 (0.30) | AOC3 | |
| SCHEMBL24823037 | 0.73 | AOC3 (0.30) | AOC3 | |
| SCHEMBL17194892 | 0.73 | TLR8 (0.44) | CHRM2CHRM3TYK2BRD4BRD3 | |
| SCHEMBL24822802 | 0.72 | ALOX5AP (0.35) | AOC3CHRM2CHRM3TYK2BRD4 | |
| SCHEMBL17809711 | 0.69 | KCNH2 (0.45) | AOC3CHRM2CHRM3BRD4BRD3 | |
| SCHEMBL24822834 | 0.68 | TYK2 (0.35) | AOC3CHRM2CHRM3TYK2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220411384-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY | 2022-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220411384-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS | TYK2, JAK2, STAT3 | AOC3 1933/4885CHRM2 4547/4885CHRM3 4532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.