SCHEMBL2482408

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2499437	0.89	RPS6KB1 (0.51)	ASPHKDM8KDM4ERIOX2RPS6KB1
	SCHEMBL2479832	0.87	RPS6KB1 (0.61)	RPS6KB1AURKAAURKBJAK3IRAK4
	SCHEMBL2482122	0.86	RPS6KB1 (0.52)	KDM4ERPS6KB1AURKAJAK3IRAK4
	SCHEMBL2479527	0.86	JAK3 (0.53)	KDM4ERPS6KB1JAK3IRAK4JAK2
	SCHEMBL2479323	0.85	JAK2 (0.51)	ASPHKDM8KDM4ERIOX2RPS6KB1
	SCHEMBL12330612	0.85	JAK3 (0.42)	ASPHKDM8KDM4ERIOX2RPS6KB1
	SCHEMBL12280211	0.85	CDC7 (0.53)	KDM4ERPS6KB1JAK3IRAK4JAK2
	SCHEMBL12456545	0.85	JAK3 (0.52)	KDM4ERPS6KB1AURKAJAK3IRAK4
	SCHEMBL12301445	0.84	RPS6KB1 (0.44)	ASPHKDM8KDM4ERIOX2RPS6KB1
	SCHEMBL2479053	0.84	KDM4E (0.51)	KDM4EJAK3IRAK4JAK2JAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.