Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2510094 | 0.87 | KMT2A (0.44) | KMT2AMEN1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL2480091 | 0.86 | KMT2A (0.48) | KMT2AMEN1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL2508926 | 0.86 | KMT2A (0.43) | KMT2AMEN1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL2483320 | 0.86 | KMT2A (0.43) | KMT2AMEN1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL2481446 | 0.85 | KMT2A (0.43) | KMT2AMEN1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL2483534 | 0.83 | KMT2A (0.45) | KMT2AMEN1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL2482517 | 0.83 | PPARG (0.47) | KMT2AMEN1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL2507768 | 0.82 | ALOX15 (0.56) | KMT2AMEN1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL2481807 | 0.81 | CYP1A2 (0.40) | KMT2AMEN1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL2499782 | 0.81 | PPARG (0.41) | KMT2AMEN1CYP3A4TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8604235-B2 | Production of substituted phenylene aromatic diesters and compositions | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-12-10 | — | — | US | disclosed |
| EP-2376423-A1 | PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS | Dow Global Technologies LLC (US) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010078519-A1 | PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-07-08 | — | — | WO | disclosed |