Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.49 |
| ▸ | CDK9 | P50750 | 1/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 9/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 9/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 4/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.39 |
| ▸ | CCND1 | P24385 | 4/20 | 0.39 |
| ▸ | CDK2 | P24941 | 4/20 | 0.39 |
| ▸ | CDK1 | P06493 | 3/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.39 |
| ▸ | CCND3 | P30281 | 2/20 | 0.39 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | IDH2 | P48735 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17148506 | 0.86 | MKNK1 (0.52) | CCNT1CDK9MKNK1MKNK2HTR3A | |
| SCHEMBL83995 | 0.85 | CDK4 (0.47) | CDK9HTR3ACDK4CCNA2CCND1 | |
| SCHEMBL14004978 | 0.85 | MAPK1 (0.57) | CCNT1CDK9MKNK1MKNK2HTR3A | |
| SCHEMBL84414 | 0.83 | CDK1 (0.54) | CCNT1CDK9MKNK2CDK4CCNA2 | |
| SCHEMBL84078 | 0.81 | CDK1 (0.56) | MKNK2CDK4CCNA2CCND1CDK2 | |
| SCHEMBL14383122 | 0.79 | CDK4 (0.59) | CCNT1CDK9MKNK1MKNK2CDK4 | |
| SCHEMBL19098459 | 0.76 | MKNK1 (0.52) | MKNK1MKNK2CCNA2CDK2IDH1 | |
| SCHEMBL21566708 | 0.75 | CCNT1 (0.49) | CCNT1CDK9MKNK1MKNK2CDK4 | |
| SCHEMBL84411 | 0.75 | CDK7 (0.50) | CCNT1CDK9MKNK1MKNK2CDK4 | |
| SCHEMBL21064115 | 0.74 | MAPK1 (0.54) | CCNT1CDK9MKNK1MKNK2CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272060-A1 | EP2 ANTAGONIST COMPOUNDS | RESERVOIR NEUROSCIENCE, INC. (US) | 2022-12-29 | — | — | WO | disclosed |