SCHEMBL24825463

SCHEMBL24825463

c1ccc2c(-c3ccc(N(c4ccc(-c5ccc6c(ccc7ccccc76)c5)cc4)c4ccc5c(c4)oc4c6ccccc6ccc54)cc3)cccc2c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 11/20 0.38
CYP1B1 Q16678 11/20 0.38
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38
ALOX5 P09917 1/20 0.36
CYP1A2 P05177 10/20 0.35
CYP3A4 P08684 2/20 0.34
TSHR P16473 2/20 0.34
CYP2C19 P33261 2/20 0.34
PRKDC P78527 2/20 0.34
KDM4E B2RXH2 1/20 0.34
PDE5A O76074 1/20 0.34
ALDH1A1 P00352 1/20 0.34
TP53 P04637 1/20 0.34
ABCB1 P08183 1/20 0.34
CYP2D6 P10635 1/20 0.34
MAPT P10636 1/20 0.34
CYP19A1 P11511 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24825418 0.95 ALOX5 (0.37) CYP1A1CYP1B1ALOX5CYP1A2CYP3A4
SCHEMBL24824985 0.94 ALOX5 (0.40) CYP1A1CYP1B1CA12CA1CA2
SCHEMBL24825239 0.94 ALOX5 (0.39) CYP1A1CYP1B1ALOX5CYP1A2CYP3A4
SCHEMBL24825663 0.93 ALOX5 (0.36) CYP1A1CYP1B1ALOX5CYP1A2CYP3A4
SCHEMBL25730853 0.93 ALOX5 (0.37) CYP1A1CYP1B1ALOX5CYP1A2CYP3A4
SCHEMBL24825168 0.93 CYP1A1 (0.40) CYP1A1CYP1B1CA12CA1CA2
SCHEMBL24825284 0.92 ALOX5 (0.40) CYP1A1CYP1B1CA12CA1CA2
SCHEMBL24825488 0.92 CYP1A1 (0.37) CYP1A1CYP1B1CA12CA1CA2
SCHEMBL24887540 0.92 ALOX5 (0.40) CYP1A1CYP1B1CA12CA1CA2
SCHEMBL24887147 0.92 CYP1A1 (0.42) CYP1A1CYP1B1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220416174-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2022-12-29 US disclosed