Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14930381 | 0.85 | LRRK2 (0.37) | — | |
| SCHEMBL18377886 | 0.81 | — | — | |
| SCHEMBL14704037 | 0.78 | CDK5 (0.38) | — | |
| SCHEMBL20325978 | 0.78 | CDK5 (0.39) | — | |
| SCHEMBL19732426 | 0.78 | HTR2A (0.35) | — | |
| SCHEMBL18250753 | 0.76 | CDK5 (0.39) | — | |
| SCHEMBL14926117 | 0.76 | KIT (0.33) | — | |
| SCHEMBL24496307 | 0.76 | AR (0.32) | — | |
| SCHEMBL24826177 | 0.76 | — | — | |
| SCHEMBL24501900 | 0.76 | CPB2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022271612-A1 | HETEROCYCLIC EGFR INHIBITORS FOR USE IN THE TREATMENT OF CANCER | BLUEPRINT MEDICINES CORPORATION (US) | 2022-12-29 | — | — | WO | disclosed |